Boston is typically 6 hours behind Paris. When it's 3:00 PM in Paris, it's 9:00 AM in Boston. Both cities observe daylight saving time, though the transition dates differ slightly.
During the brief periods when the US and France change clocks on different weekends (usually in March and November), the difference can temporarily be 5 or 7 hours. For most of the year, it's a consistent 6-hour difference.
Optimal meeting window: 8:00 AM - 11:00 AM Boston time (2:00 PM - 5:00 PM Paris). This catches afternoon business hours in Paris while being morning in Boston.
Boston's universities and biotech companies frequently coordinate with French research institutions during this window.