San Francisco is 2 hours behind Chicago. When it's 12:00 PM in Chicago, it's 10:00 AM in San Francisco. Both cities observe DST, maintaining the 2-hour difference year-round.
Chicago uses CT (Central Time) while San Francisco uses PT (Pacific Time).
Optimal window: 10:00 AM - 6:00 PM Chicago time (8:00 AM - 4:00 PM San Francisco). This covers standard business hours in both cities.
Chicago and San Francisco are major tech and financial hubs with extensive business travel between them.