London is typically 5 hours ahead of Indianapolis. When it's 12:00 PM in London, it's 7:00 AM in Indianapolis. Both cities observe DST but on different schedules.
During DST transitions (2-3 weeks in March and November), the difference can be 4 or 6 hours. Indianapolis uses EST/EDT, London uses GMT/BST.
Afternoon London works best! 1:00 PM - 6:00 PM London corresponds to 8:00 AM - 1:00 PM Indianapolis. Good business overlap.
Indianapolis is known for the Indy 500 and is a major pharmaceutical hub, home to Eli Lilly. The city is also a significant logistics center due to its central US location.