San Diego is typically 8 hours behind London. When it's 6:00 PM in London, it's 10:00 AM in San Diego. Both cities observe daylight saving time, but they switch on slightly different schedules.
During most of the year, the difference is 8 hours. During the brief periods when US and UK DST schedules don't align (early March and late October/early November), the difference can be 7 or 9 hours.
Optimal meeting window: 7:00 AM - 9:00 AM San Diego time (3:00 PM - 5:00 PM London). Early morning San Diego catches afternoon London before end of business.
San Diego's biotech and defense industries have connections to UK companies. The city is home to major research institutions and defense contractors that collaborate with British partners.