Santiago is 5 hours ahead of Los Angeles during Chile's summer/LA's winter. Santiago uses Chile Summer Time (CLST, UTC-3) while Los Angeles uses Pacific Standard Time (PST, UTC-8). When it's 12:00 PM in Los Angeles, it's 5:00 PM in Santiago.
The difference varies as both cities observe daylight saving time at different times (opposite seasons). During Northern Hemisphere summer, the difference may be as little as 3 hours.
Best calling time: 8:00 AM - 12:00 PM Los Angeles time. This covers Santiago's afternoon business hours regardless of season.
Santiago and Los Angeles are both on the Pacific coast with growing business connections. Chile is a major trading partner on the US West Coast for mining and agriculture. Direct flights connect them in about 11 hours.