Santiago is 4-5 hours behind Madrid. The exact difference varies because both cities observe DST but in opposite seasons. Madrid uses CET/CEST (UTC+1/+2) while Santiago uses CLT/CLST (UTC-4/-3).
Spain and Chile share strong economic and cultural ties, with Spanish as the common language. Chile has one of the largest Spanish populations in South America.
Early afternoon in Madrid works well. 2:00 PM Madrid is around 9:00 AM or 10:00 AM Santiago - ideal for business hours overlap.
Iberia and LATAM operate direct flights between Madrid and Santiago, taking about 13 hours. Chile is a major destination for Spanish investment in Latin America.