Madrid is 4-5 hours ahead of Sao Paulo. Sao Paulo uses Brasilia Time (BRT, UTC-3) while Madrid uses Central European Time (CET/CEST, UTC+1/+2). When it's 12:00 PM in Sao Paulo, it's 4:00 PM or 5:00 PM in Madrid.
Brazil no longer observes daylight saving time (since 2019), while Spain does. The difference varies from 4 hours (winter) to 5 hours (summer).
Best calling time: 9:00 AM - 2:00 PM Sao Paulo time. This corresponds to 1:00 PM - 6:00 PM in Madrid, covering afternoon business hours.
Sao Paulo and Madrid share deep cultural ties through Brazil's colonial history and ongoing business relationships. LATAM and Iberia operate extensive flight networks between them.